What is the strongest argument against a new Constitution?

Thomas Jefferson once said that every generation should write its own Constitution. While that might be an extreme view, ten or more generations have now passed without adopting a new Constitution.

Address each part of the prompt:

Should the United States call a new Constitutional Convention?
What is the strongest argument in favor of a new Constitution?
What is the strongest argument against a new Constitution?
If we had a new Constitution, what is the top thing that you would want to change?

Background Materials

1. OpenStax, Chapter 2 Links to an external site.. https://openstax.org/books/american-government-3e/pages/2-introduction

2. Clay S. Jenkinson, “Is it Time for a New Constitutional Convention? Links to an external site.” (Governing, July 2022).
https://www.governing.com/context/is-it-time-for-a-new-constitutional-convention
3. National Constitution Center, “The Constitution Drafting Project. Links to an external site.”
https://constitutioncenter.org/news-debate/special-projects/constitution-drafting-project