Explains studies which found that psilocybin can be used to effectively treat alcoholism, depression, anxiety, other substance abuse disorders.

Resources:

• Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367557/pdf/10.1177_0269881116675513.pdf

• Psychedelics and Psychedelic-Assisted Psychotherapy (review) https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2019.19010035

◦ Use this source to discuss mechanism of psilocybin

Explains studies which found that psilocybin can be used to effectively treat alcoholism, depression, anxiety, other substance abuse disorders

• Trial of Psilocybin versus Escitalopram (Lexapro) for Depression (clinical trial) https://www-nejm-org.libproxy.uoregon.edu/doi/pdf/10.1056%2FNEJMoa2032994

• Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder (clinical trial) https://pubmed.ncbi.nlm.nih.gov/17196053/

• Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression (clinical trial) https://pubmed.ncbi.nlm.nih.gov/31941394/

• Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

https://link.springer.com/content/pdf/10.1007/s00213-017-4771-x.pdf

• Psilocybin-assisted mindfulness training modulates self-consciousness and brain default mode network connectivity with lasting effects

https://pdf.sciencedirectassets.com/272508/1-s2.0-S1053811919X0009
• Article that addresses the combination of psilocybin and mindfulness therapy to improve outcomes in mental health treatment