Essay Instructions: (metoprolol)
1. Select a patient condition that you are interested in.
2. Select one medication that is commonly prescribed for this condition. （medication chosen here is Metoprolol）
3. Explain the pharmacodynamics and mechanism of action of this medication for this condition.
4. Discuss two significant adverse medication events for your chosen medication.
5. Support instructions 3 and 4 with two high quality research articles (contemporary less than 5 years old) that discuss the therapeutic risks and benefits of this medication for this condition.
6. *Identify TWO pharmacokinetic concepts that is significant for your selected drug.
7. In your own words, explain these pharmacokinetic concepts and why it is significant for your selected medication.
*Examples of pharmacokinetic concepts: acid labile, first pass or pre-systemic metabolism, protein binding, the volume of distribution, tissue binding, biotransformation, enterohepatic recycling, plasma half-life, elimination half-life, active metabolites, prodrug, renal excretion
8. 2000 words, APA 7 references, contemporary references less than 5 years old.
Marking criteria:
This assessment task relates to the following learning outcomes:
LO 1 – Apply pharmacokinetic and pharmacodynamic principles to the therapeutic indications for selected medications.
LO 3 – Critically analyse the contributors to, and presentation of, adverse medication events.
LO 4 – Critically apply research evidence to support the therapeutic use of a medication/medication regimen.
LO 5 – Present work at the appropriate academic standard.
